Genetic Testing

Genetic Testing

Genetic testing is a powerful tool to help us to understand our health and ourselves.  Guided by their excellence, the genetic information that they offer, and their strict confidentiality, UP!health has selected European Nordic Labs to provide our genetic testing services.

 

EXCELLENCE

Founded in 1998 with the goal to provide patients and practitioners with clear and reliable laboratory test results, Nordic Laboratories have since become a leading European laboratory test distributor. Operating completely independently, they select laboratory assessments from a wide range of suppliers, based on the individual quality and value of each test.

 

GENETIC PANELS

UP!health offers a series of genetic panels;

  • DNA Health
  • DNA Sport
  • DNA Health
  • DNA Oestrogen

We believe that these panels provide the most health-focused information available today, informing you and your practitioner about the most effective ways in which to optimise your health.

 

REPORTS

Our naturopath Sara Jefferson combines her understanding of your individual health history and body condition to offer you an in-depth report that focuses on maintaining and improving your health and vitality. The report will include:

  • The impact level of any genetic variants identified;
  • An explanation of their impact on your health;
  • Appropriate nutrition and lifestyle recommendations.

 

CONFIDENTIALITY

Although many tests are now accessible online, your data is collected with the possibility of being made public, or disclosed to associated parties.

Nordic Labs guarantees complete confidentiality, along with the assurance that your results will never be included in public data banks. UP!health takes the extra step of encrypting all data that leaves the clinic to the lab for testing, ensuring that  no personal reference will be on your sample for the ultimate in confidentiality.

 

DNA HEALTH

The DNA Health panel is designed to optimise health and wellbeing by personalising your lifestyle and diet choices, and where necessary, recommending supplements tailored to offset any particular nutritional deficit based on your specific gene variants.

 

WHAT IT IS

DNA Health grounds patient treatment in gene-based personalised nutrition, with 26 tested genes marked for seven key biological processes. Results provide a blueprint for a gene-based healthy eating plan; dietary goals for relevant vitamins, minerals, phytochemicals, and foods, along with nutritional supplement recommendations. With this genetic knowledge, practitioners can provide specific diet and lifestyle recommendations most favourable to a patient’s genes.

 

WHAT IT TESTS

26 gene variants related to:

  • Heart disease – the impact of cholesterol and the risk of cardiovascular disease.
  • B Vitamins – Vitamins B6, B12 and Folate are all involved in DNA and cell renewal, the production of neurotransmitters and detoxifying agents.
  • Oxidative stress – the biological response to internal and external stresses.
  • Bone Health – identifying Calcium and vitamin D metabolic processes.
  • Detoxification – highlighting the body’s ability to rid itself of waste and pollutants.
  • Inflammation – response to injury, infection and allergies.
  • Insulin resistance – highlighting any predisposition to sugar-related illnesses.

 

WHO IT’S FOR

DNA Health is of value to anybody looking for a genetic basis for his or her health and associated treatments. The analysis is comprehensive enough to cover many health risks, providing clear interpretations for lifestyle response.

TIP:  This screening makes a great birth gift, as an individual’s genetic information remains the same throughout their life.

 

DNA SPORT

WHAT IS IT

DNA Sport unlocks the genetic basis for performance potential in both elite and recreational athletes. The focus is on achieving the maximum return from your training. Related genes are tested for three categories:

  • Power and endurance;
  • Tendon pathology;

The result creates a specific profile for exercise selection, recovery methods, and injury avoidance. This profile is of particular interest to athletes who have achieved results below their expectations, as the key to their performance lies within their genes.

WHAT IT TESTS

Three keys to fitness:

  • Strength and endurance – physiological factors including:
    • circulatory and cardiovascular performance;
    • blood pressure; heart and lung capacity;
    • muscle strength;
    • adaptation to training.
  • Connective tissues – the chance of soft tissue injury.
  • Recovery time – an athlete’s sensitivity to inflammation, free radicals, and oxidative stress.

 

WHO IT’S FOR

DNA Sport is aimed at both the elite and the recreational athlete looking to gain the maximum return from their training. Whether pursuing a marathon best, or just seeking to finish their first race, DNA Sport gives the key to unlocking athletic potential.

 

DNA DIET

WHAT IT IS

DNA Diet helps optimise diet and exercise interventions in order to treat and prevent obesity. Results provide personal diet, exercise and lifestyle strategies for both the patient and their practitioner.

 

WHAT IT TESTS

13 genes that mark for individual disposition to:

  • Diet
  • Energy adaptation
  • Weight gain
  • Exercise
  • Circadian rhythm
  • Weight loss training.

 

WHO IT’S FOR

DNA Diet is primarily intended for patients with weight loss or weight management issues, however individuals of a healthy weight can likewise benefit from the nutritive profile and dietary recommendations.

 

DNA OESTROGEN

WHAT IT IS

More than 80% of breast cancer occurs in women with no family history of the disease. [1,2]. Oestrogen affects the function of a number of target tissues, and research has shown that an increased lifetime exposure to oestrogen is a strong risk factor in the development of breast cancer.

DNA Oestrogen includes 11 genes involved in oestrogen production, metabolism and detoxification, providing information to guide personalised diet, lifestyle, hormone, and nutraceutical recommendations.

 

WHAT IT TESTS

11 genes that mark for individual sensitivity to:

  • dietary and environmental sources of oestrogen;
  • oestrogen metabolism and detoxification.

 

WHO IT’S FOR

  • Men or women with a strong family history of breast, ovarian, colon or prostate cancer;
  • Women who suffer from oestrogen-dominant conditions such as endometriosis, premenstrual syndrome and uterine fibroid tumours;
  • Women considering oral contraceptives, hormone replacement therapy or bio-identical hormone supplementation;
  • Women who are considering in-vitro fertilization or who have been diagnosed with oestrogen receptor-positive breast cancer.

 

REFERENCES

  1. Collaborative Group on Hormonal Factors in Breast Cancer. Familial breast cancer: collaborative reanalysis of individual data from 52 epidemiological studies including 58,209 women with breast cancer and 101,986 women without the disease. Lancet. 358: 1389-99, 2001.
  2. Kharazmi E, Chen T, Narod S, Sundquist K, Hemminki K. Effect of multiplicity, laterality, and age at onset of breast cancer on familial risk of breast cancer: a nationwide prospective cohort study. Breast Cancer Res Treat. 144(1):185-92, 2014.